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. 2022 Jun;45(6):1001-1007.
doi: 10.1038/s41440-022-00899-z.

Pulse transit time-estimated blood pressure: a comparison of beat-to-beat and intermittent measurement

Satoshi Hoshide  1 , Akiomi Yoshihisa  2   3 , Fumihiro Tsuchida  4 , Hiroyuki Mizuno  1 , Hiroki Teragawa  5 , Takatoshi Kasai  6 , Hitoshi Koito  7 , Shin-Ichi Ando  8 , Yoshihiko Watanabe  9 , Yasuchika Takeishi  2 , Kazuomi Kario  10
Affiliations

Pulse transit time-estimated blood pressure: a comparison of beat-to-beat and intermittent measurement

Satoshi Hoshide et al. Hypertens Res. 2022 Jun.

Abstract

Pulse transit time (PTT), which refers to the travel time between two arterial sites within the same cardiac cycle, has been developed as a novel cuffless form of continuous blood pressure (BP) monitoring. The aim of this study was to investigate differences in BP parameters, including BP variability, between those assessed by beat-to-beat PTT-estimated BP (eBPBTB) and those assessed by intermittent PTT-estimated BP at fixed time intervals (eBPINT) in patients suspected of having sleep disordered breathing (SDB). In 330 patients with SDB (average age, 66.8 ± 11.9 years; 3% oxygen desaturation index [ODI], 21.0 ± 15.0/h) from 8 institutes, PTT-estimated BP was continuously recorded during the nighttime. The average systolic eBPBTB, maximum systolic and diastolic eBPBTB, standard deviation (SD) of systolic and diastolic eBPBTB, and coefficient variation (CV) of systolic and diastolic eBPBTB were higher than the respective values of eBPINT (all P < 0.05). Bland-Altman analysis showed a close agreement between eBPBTB and eBPINT in average systolic BP and SD and CV of systolic BP, while there were disagreements in both minimum and maximum values of eBPBTB and eBPINT in patients with high systolic BP (P < 0.05). Although systolic BP variability incrementally increased according to the tertiles of 3%ODI in both eBPBTB and eBPINT (all P < 0.05), there was no difference in this tendency between eBPBTB and eBPINT. In patients with suspected SDB, the difference between eBPBTB and eBPINT was minimal, and there were disagreements regarding both the minimum and maximum BP. However, there were agreements in regard to the index of BP variability between eBPBTB and eBPINT.

Keywords: Beat-to-beat; Blood pressure variability; Continuous blood pressure monitoring; Pulse transit time.

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Conflict of interest statement

TK is affiliated with a department endowed by Philips Respironics, ResMed, and Fukuda Denshi.

Figures

Fig. 1
Fig. 1
Bland–Altman plots comparing systolic blood pressure parameters between eBPBTB with eBPINT. eBPBTB indicates beat-to-beat PTT-estimated BP, eBPINT intermittent PTT-estimated BP at fixed time intervals
See this image and copyright information in PMC

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