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Review
. 1986;44(3):296-9.

[D-penicillamine and collagen]

[Article in French]
J P Camus, A C Koeger
  • PMID: 3538948
Review

[D-penicillamine and collagen]

[Article in French]
J P Camus et al. Ann Biol Clin (Paris). 1986.

Abstract

D-penicillamin is widely used for the treatment of various diseases, such as cystinuria. Wilson's disease or rheumatoid arthritis. It is an osteolathyrogenic agent. This effect may explain some side-effects such as fetal dysplasias, wound healing defects, skin lesions, obliterative bronchiolitis, auto-immune abnormalities. Conversely the collagen effects of D-Penicillamin explain its use in various fibrosis states such as progressive systemic sclerosis, liver or lung fibrosis.

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