Unlocking the secrets to Janus kinase activation
- PMID: 35389811
- DOI: 10.1126/science.abo7788
Unlocking the secrets to Janus kinase activation
Abstract
The full-length structure of a Janus kinase provides insights for drug development.
Comment on
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Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation.Science. 2022 Apr 8;376(6589):163-169. doi: 10.1126/science.abn8933. Epub 2022 Mar 10. Science. 2022. PMID: 35271300 Free PMC article.
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