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Comment
. 2022 Apr 6;110(7):1090-1092.
doi: 10.1016/j.neuron.2022.03.017.

Immune genes outside immune cells for multiple sclerosis

Na Sun  1 , Manolis Kellis  2
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Free article
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Immune genes outside immune cells for multiple sclerosis

Na Sun et al. Neuron. .
Free article

Abstract

In this issue of Neuron, Meijer and Agirre et al. (2022) demonstrate that immune genes exhibit a primed chromatin state in healthy oligodendroglia and are transcriptionally activated in MS through a series of epigenetic activations including histone modification deposition, transcription factor binding, and chromatin reconfiguration.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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