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Comment
. 2022 Apr 6;110(7):1097-1099.
doi: 10.1016/j.neuron.2022.03.027.

Brain metastases: Not all tumors are created equal

Daniel Kirschenbaum  1 , Ido Amit  2
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Free article
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Brain metastases: Not all tumors are created equal

Daniel Kirschenbaum et al. Neuron. .
Free article

Abstract

Metastases are the main cause of death in cancer patients. In a recent issue of Cell, Gonzalez et al. (2022) analyze gene expression on the single-cell level in brain metastases from various primary tumors. By profiling metastatic tumor cells and their niche, they demonstrate distinctive and shared features across metastases.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

Comment on

  • Cellular architecture of human brain metastases.
    Gonzalez H, Mei W, Robles I, Hagerling C, Allen BM, Hauge Okholm TL, Nanjaraj A, Verbeek T, Kalavacherla S, van Gogh M, Georgiou S, Daras M, Phillips JJ, Spitzer MH, Roose JP, Werb Z. Gonzalez H, et al. Cell. 2022 Feb 17;185(4):729-745.e20. doi: 10.1016/j.cell.2021.12.043. Epub 2022 Jan 20. Cell. 2022. PMID: 35063085 Free PMC article.

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