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Review
. 2021 Jun;22(6):61-66.
doi: 10.1007/s11882-022-01032-3. Epub 2022 Apr 8.

Real-World LEAP Implementation

Jennifer J Koplin  1   2 , Victoria X Soriano  3   4 , Rachel L Peters  3   4
Affiliations
Review

Real-World LEAP Implementation

Jennifer J Koplin et al. Curr Allergy Asthma Rep. 2021 Jun.

Abstract

Purpose of review: In 2015, findings from the Learning Early About Peanut allergy (LEAP) trial provided the first convincing evidence that peanut allergy may be preventable through early peanut introduction into the infant diet. Here we discuss implementation of the LEAP study findings around the world and emerging evidence of the impacts on infant feeding and food allergy.

Recent findings: The LEAP findings led to rapid changes in allergy prevention guidelines internationally to recommend early peanut introduction. There is now emerging evidence that this has been followed by a substantial increase in early peanut introduction to infants. Studies investigating the impact of these changes in infant feeding practices on the prevalence of peanut allergy are underway. The LEAP trial represented a significant step forwards in food allergy prevention and new research over the past 5 years has provided insights into how best to implement this intervention in the real world.

Keywords: Complementary foods; Early introduction; Egg allergy; Food allergy; Peanut allergy; Prevention.

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Conflict of interest statement

Jennifer J. Koplin and Victoria X. Soriano declare that they have no conflict of interest.

References

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