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Review
. 2022 May 10;145(19):e1037-e1052.
doi: 10.1161/CIR.0000000000001064. Epub 2022 Apr 11.

SARS-CoV-2 Infection and Associated Cardiovascular Manifestations and Complications in Children and Young Adults: A Scientific Statement From the American Heart Association

Pei-Ni Jone, Anitha John, Matthew E Oster, Kiona Allen, Adrianna H Tremoulet, Elizabeth V Saarel, Linda M Lambert, Shelley D Miyamoto, Sarah D de Ferranti; American Heart Association Leadership Committee and Congenital Cardiac Defects Committee of the Council on Lifelong Congenital Heart Disease and Heart Health in the Young; Council on Hypertension, and Council on Peripheral Vascular Disease
Free article
Review

SARS-CoV-2 Infection and Associated Cardiovascular Manifestations and Complications in Children and Young Adults: A Scientific Statement From the American Heart Association

Pei-Ni Jone et al. Circulation. .
Free article

Abstract

Coronavirus disease 2019 (COVID-19) resulted in a global pandemic and has overwhelmed health care systems worldwide. In this scientific statement, we describe the epidemiology, pathophysiology, clinical presentations, treatment, and outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and multisystem inflammatory syndrome in children and young adults with a focus on cardiovascular manifestations and complications. We review current knowledge about the health consequences of this illness in children and young adults with congenital and acquired heart disease, the public health burden and health disparities of this infection in these populations, and vaccine-associated myocarditis.

Keywords: AHA Scientific Statements; COVID-19; SARS-CoV-2; child; multisystem inflammatory syndrome in children; treatment outcome; young adult.

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