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Case Reports
. 2022 Feb 1;56(1):39-41.
eCollection 2022 Feb.

Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE): a rare presentation and case report

Thaneraj SahanaPushpa  1 , Rajendran Balamurugan  2
Affiliations
Case Reports

Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE): a rare presentation and case report

Thaneraj SahanaPushpa et al. Can J Dent Hyg. .

Abstract
in English, French

Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is a rare, benign, and self-limiting ulcerative lesion, with the tongue being the most common site of occurrence and traumatic inflictions being the common etiology. Case report: A 45-year-old female reported to the dental operatory with a complaint of pain on the left side of her tongue for the past 8 months. Her history revealed that a small ulcer had gradually grown to be 2 cm x 1.5 cm on presentation. She indicated that the ulcer often interfered with her maxillary left canine while occluding. She also gave a history of a tobacco chewing habit for 15 years which she stopped 6 years ago. Clinically she had a single erythematous ulcer with irregular borders and raised margins. The client was treated with surgical excision of the lesion. The excised lesion was confirmed histologically to have eosinophil rich cells and was diagnosed as TUGSE. Conclusion: TUGSE should be recognized and not neglected as it closely resembles malignancies of the oral cavity. It also has a good prognosis and heals rapidly after the surgical excision or on its own with time, which may range from a few weeks to a year.

Le granulome ulcératif traumatique avec éosinophilie stromale (TUGSE) est une lésion ulcérative rare, bénigne et spontanément résolutive, la langue étant la zone d'occurrence la plus fréquente et les inflictions traumatiques étant l'étiologie la plus courante. Rapport de cas : Une femme de 45 ans s'est présentée à la salle de traitement dentaire en se plaignant d'une douleur du côté gauche de sa langue depuis les 8 derniers mois. Ses antécédents ont révélé qu'un petit ulcère avait progressivement grossi jusqu'à présenter une taille de 2 cm x 1,5 cm. Elle a signalé que l'ulcère entravait souvent sa canine maxillaire gauche lorsque ses dents étaient en occlusion. Elle a aussi fait état d'une habitude de mastication de tabac pendant 15 ans, ce qu'elle a abandonné il y a 6 ans. Elle présentait cliniquement un seul ulcère érythémateux aux contours irréguliers et des marges surélevées. La cliente a été traitée par excision chirurgicale de la lésion. Une analyse histologique de la lésion excisée a confirmé la présence de cellules riches en éosinophiles et a été diagnostiquée comme étant un TUGSE. Conclusion : Le TUGSE doit être constaté et ne pas être négligé, puisqu'il ressemble de près aux tumeurs malignes de la cavité buccale. De plus, son pronostic est bon et il guérit rapidement après l'excision chirurgicale ou par lui-même avec le temps, qui peut varier de quelques semaines à une année.

Keywords: TUGSE; squamous cell carcinoma; tongue.

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Conflict of interest statement

The authors have declared no conflicts of interest.

Figures

Figure 1.
Figure 1.
Clinical image showing ulceration in the left lateral border of the tongue
Figure 2.
Figure 2.
Section showing ulcerated epithelium and dense inflammatory cell infiltrate in connective tissue (standard magnification 10x)
Figure 3.
Figure 3.
Section showing chronic inflammatory cells such as lymphocytes, plasma cells, and eosinophils (standard magnification 40x)
See this image and copyright information in PMC

References

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