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Review
. 2022 Mar 25:12:858155.
doi: 10.3389/fcimb.2022.858155. eCollection 2022.

Research Progress on the Correlation Between Gardnerella Typing and Bacterial Vaginosis

Hanyu Qin  1 , Bingbing Xiao  1
Affiliations
Review

Research Progress on the Correlation Between Gardnerella Typing and Bacterial Vaginosis

Hanyu Qin et al. Front Cell Infect Microbiol. .

Abstract

Bacterial vaginosis (BV) is the most common infectious disease of the reproductive tract in women of childbearing age. It often manifests as an imbalance in the vaginal microbiome, including a decrease in Lactobacillus and an increase in anaerobic bacteria. While Gardnerella spp. are considered a major cause of BV, they are also detected in the vaginal microbiome of healthy women. G. vaginalis was the only recognized species of Gardnerella until a recent study characterized three new species, G. leopoldii, G. piotii, and G. swidsinskii. This review describes the different types and genetic diversity of Gardnerella, as well as new findings on the correlation between different Gardnerella spp. and BV.

Keywords: Gardnerella; bacterial vaginosis; clinical outcomes; cpn-60; qPCR; subtypes; whole genome sequencing.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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