Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Jun;19(2):279-303.
doi: 10.1177/17423953221089309. Epub 2022 Apr 11.

A systematic review on physical function, activities of daily living and health-related quality of life in COVID-19 survivors

Affiliations

A systematic review on physical function, activities of daily living and health-related quality of life in COVID-19 survivors

Katna de Oliveira Almeida et al. Chronic Illn. 2023 Jun.

Abstract

Objective: To analyze the published studies that investigated the physical function, activities of daily living and health-related quality of life in COVID-19 survivors.

Design: Systematic review.

Methods: We searched MEDLINE/PubMed, Scopus, SciELO, and Cochrane Library for studies that evaluated the physical function, activities of daily living and health-related quality of life after COVID-19 from the earliest date available to July 2021. Two independent reviewers screened and selected the studies. The Newcastle Ottawa Scale was used to evaluate methodological quality.

Results: We included 35 studies in this systematic review. Of the 35 studies included, 28 were cohort, and 7 cross-sectional studies The studies demonstrated that COVID-19 survivors had reduced levels of physical function, activities of daily living, and health-related quality of life. Furthermore, incomplete recovery of physical function, and performance in activities of daily living were observed 1 to 6 months post-infection.

Discussion: Physical disability and reduction in health-related quality of life is a common condition in post-COVID-19 and impairments may persist up to 1 to 6 months. Researchers and clinicians can use these findings to understand the potential disabilities and rehabilitation needs of people recovering from the COVID-19.

Keywords: COVID-19; disability and health; international classification of functioning; post-acute COVID-19 syndrome; quality of life.

PubMed Disclaimer

Conflict of interest statement

The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Search and selection of studies for systematic review according to PRISMA.

Similar articles

Cited by

References

    1. De Sire A, Andrenelli E, Negrini Fet al.et al.International multiprofessional steering committee of cochrane rehabilitation REH-COVER action. Rehabilitation and COVID-19: a rapid living systematic review by Cochrane rehabilitation field updated as of December 31st, 2020 and synthesis of the scientific literature of 2020. Eur J Phys Rehabil Med 2021. DOI: 10.23736/S1973-9087.21.06870 - DOI - PubMed
    1. Kiekens C, Boldrini P, Andreoli A, et al.Rehabilitation and respiratory management in the acute and early post-acute phase. “Instant paper from the field” on rehabilitation answers to the COVID-19 emergency. Eur J Phys Rehabil Med 2020; 56: 323–326. - PubMed
    1. Rodriguez-Morales AJ, Cardona-Ospina JA, Gutiérrez-Ocampo E, et al.Clinical, laboratory and imaging features of COVID-19: a systematic review and meta-analysis. Travel Med Infect Dis 2020; 34: 1–13. - PMC - PubMed
    1. Palayew A, Norgaard O, Safreed-Harmon Ket al.et al.Pandemic publishing poses a new COVID-19 challenge. Nat Hum Behav 2020; 4: 666–669. - PubMed
    1. Borges do Nascimento IJ, Cacic N, Abdulazeem HM, et al.Novel coronavirus infection (COVID-19) in humans: a scoping review and meta-analysis. J Clin Med 2020; 9: 41. - PMC - PubMed

Publication types