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. 2022 Jun 1;97(6):679-681.
doi: 10.1002/ajh.26567. Epub 2022 Apr 19.

Magnetic resonance imaging metrics of oxygen extraction fraction: Contradictions or insight into pathophysiological mechanisms?

Jeffrey N Stout  1 , Pei-Yi Lin  1 , Jason Sutin  1 , John Higgins  2 , P Ellen Grant  1
Affiliations

Magnetic resonance imaging metrics of oxygen extraction fraction: Contradictions or insight into pathophysiological mechanisms?

Jeffrey N Stout et al. Am J Hematol. .

Erratum in

  • CORRIGENDUM.
    [No authors listed] [No authors listed] Am J Hematol. 2023 Sep;98(9):1503. doi: 10.1002/ajh.26986. Epub 2023 Jun 14. Am J Hematol. 2023. PMID: 37314236 No abstract available.
No abstract available

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Figures

FIGURE 1
FIGURE 1
(A) The naive picture where vessel size defines vessel type and each type is distinct and homogeneous with arterioles in red, capillaries in green and venules in blue. (B) An actual observation using two-photon microscopy of the pO2 in the vessels with pO2 heterogeneity in the capillary bed and counterintuitive higher pO2 in the venule (arrow). Scale bars, 200 μm. From Reference [6] [Color figure can be viewed at wileyonlinelibrary.com]
See this image and copyright information in PMC

References

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    1. An H, Lin W. Impact of intravascular signal on quantitative measures of cerebral oxygen extraction and blood volume under normo- and hypercapnic conditions using an asymmetric spin echo approach. Magn Reson Med 2003;50(4):708–716. - PubMed
    1. Bush A, Vu C, Choi S, et al. Calibration of T2 oximetry MRI for subjects with sickle cell disease. Magn Reson Med 2021;86(2):1019–1028. - PMC - PubMed