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Review
. 2022 Apr 6;11(7):2051.
doi: 10.3390/jcm11072051.

Diagnosis and Intervention in Early Psoriatic Arthritis

Tomoyuki Hioki  1   2 , Mayumi Komine  2 , Mamitaro Ohtsuki  2
Affiliations
Review

Diagnosis and Intervention in Early Psoriatic Arthritis

Tomoyuki Hioki et al. J Clin Med. .

Abstract

Psoriatic arthritis (PsA) is a chronic inflammatory disorder that affects approximately 20-30% of patients with psoriasis. PsA causes deformities and joint damage, impairing quality of life and causing long-term functional disability. Several recent studies demonstrated that early diagnosis and intervention for PsA prevents permanent invalidity. However, the clinical features of PsA vary and are shared with other differential diseases, such as reactive arthritis, osteoarthritis, and ankylosing spondylitis. The common and overlapping features among these diseases complicate the accurate early diagnosis and intervention of PsA. Therefore, this review focuses on the current knowledge of the diagnosis of early PsA and discusses the meaning of early intervention for early PsA.

Keywords: early diagnosis; early intervention; psoriatic arthritis; treatment.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
The natural clinical course of PsA, including its preclinical stages. Each stage can be reversed as represented by the two-way arrows. Adapted from Pennington and Fitzgerald [26], Frontiers in Medicine 2021 with permission.
See this image and copyright information in PMC

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