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Review
. 2022 Apr 6;19(7):4412.
doi: 10.3390/ijerph19074412.

Experts' Opinion for Improving Pertussis Vaccination Rates in Adolescents and Adults: A Call to Action

Affiliations
Review

Experts' Opinion for Improving Pertussis Vaccination Rates in Adolescents and Adults: A Call to Action

Giovanni Gabutti et al. Int J Environ Res Public Health. .

Abstract

This article highlights the importance of diphtheria-tetanus-acellular pertussis (with reduced antigen content, dTap) vaccination in preventing pertussis, a respiratory infection that is still widespread and easily transmitted. In particular, it highlights the need to receive a booster vaccination throughout life to maintain high antibody levels, which decrease through time. This document collects the opinions that emerged from the comparison between major Italian experts in the field of vaccination. This working group was created to promote a "call to action", aimed at raising awareness among all institutions, public health authorities, and health workers involved in the vaccination process, about the importance of dTap vaccine administration and with the mindset of implementing the strategic vaccination plan provided by the National Vaccine Plan (NVP). In fact, despite this vaccine being included in the NVP, there are some issues attributable to the practice of vaccination (local health authorities, vaccination centers, occupational health services, gynecology centers, societies of work). Therefore, it is necessary that the Ministry defines the vaccination coverage objectives, identifies the groups of subjects who should receive the booster vaccine (subjects exposed to greater risk of infection, subjects over 60, pregnant women), and applies all the necessary measures to encourage the implementation of this practice.

Keywords: dTap vaccine; pertussis; pertussis booster for adults; pertussis immunity duration; pertussis immunization; pertussis vaccine; pertussis vaccine in pregnancy.

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Conflict of interest statement

All the authors declare that they received a grant from Sanofi for writing this paper. G.G. reports grants from Sanofi Pasteur MSD, GSK Biologicals SA, Pfizer, Sanofi Pasteur Italy, MSD Italy, Emergent BioSolutions, and Seqirus for taking part in advisory boards, expert meetings, acting as a speaker and/or organizer of meetings/congresses, and acting as principal investigator and chief of OU in RCTs. P.D. declares grants from DiaSorin Spa, Med-Ex Learning, Sanofi Spa, and Sintesi Spa for taking part in advisory boards/expert meetings, acting as a speaker and/or organizer of meetings/congresses, and professional advice and scientific consulting. IC, SG, and CC declare no conflicts of interest. M.C. reports grants from Pfizer, GSK, Sanofi, MSD, and Seqirus for taking part in advisory boards and meetings/congresses.

References

    1. Cherry J.D. The epidemiology of pertussis: A comparison of the epidemiology of the disease pertussis with the epidemiology of Bordetella pertussis infection. Pediatrics. 2005;115:1422–1427. doi: 10.1542/peds.2004-2648. - DOI - PubMed
    1. European Centre for Disease Prevention and Control Expert Consultation on Pertussis. 2014. [(accessed on 23 September 2021)]. Available online: https://www.ecdc.europa.eu/en/publications-data/expert-consultation-pert....
    1. Center for Disease Control and Prevention Epidemiology and Prevention of Vaccine-Preventable Diseases. [(accessed on 15 December 2021)];2015 Available online: https://www.cdc.gov/vaccines/pubs/pinkbook/index.html.
    1. Kilgore P.E., Salim A.M., Zervos M.J., Schmitt H.J. Pertussis: Microbiology, Disease, Treatment, and Prevention. Clin. Microbiol. Rev. 2016;29:449–486. doi: 10.1128/CMR.00083-15. - DOI - PMC - PubMed
    1. Center for Disease Control and Prevention Pertussis (Whooping Cough) Fast Facts. [(accessed on 23 March 2021)];2017 Available online: https://www.cdc.gov/pertussis/fast-facts.html.

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