Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Aug 1;68(8):996-1001.
doi: 10.1097/MAT.0000000000001685. Epub 2022 Apr 12.

First Use of a New Extracorporeal Membrane Oxygenation System in COVID19-Associated Adult Respiratory Distress Syndrome: The MobyBox Device

Miriam Kau  1 , Jens C Steltner  1 , Philipp M Lepper  2 , Albert J Omlor  2 , Sebastian Mang  2 , Jovan Misic  3 , Ali A Peivandi  3 , Ralf M Muellenbach  1 , Christian Reyher  1
Affiliations

First Use of a New Extracorporeal Membrane Oxygenation System in COVID19-Associated Adult Respiratory Distress Syndrome: The MobyBox Device

Miriam Kau et al. ASAIO J. .

Abstract

In late 2020, during the second wave of COVID-19 in Germany, we started using the MobyBox, which is a novel fully pneumatically driven ECMO device, on a regular basis to meet the increasing demand for ECMO therapy. In this case series, we performed a retrospective chart review of seven patients with severe COVID-19-related acute respiratory distress syndrome (ARDS) requiring veno-venous (vv)-ECMO support with the MobyBox. During ECMO treatments we have observed no disadvantages in comparison to conventional ECMO systems. There were no system failures or adverse events directly attributable to the MobyBox system. Our data support that providing vv-ECMO with the MobyBox device is safe and feasible. Furthermore, our findings suggest that the MobyBox device might represent an advantage in terms of biocompatibility. Therefore, more data on this issue is needed to better understand how the pneumatically driven pump affects cellular blood components.

PubMed Disclaimer

Conflict of interest statement

Disclosure: R.M.M. has been in the medical advisory board of Hemovent. The remaining authors have no conflicts of interest to disclose.

References

    1. "Solutions: The MobyBox." Hemovent website, Hemovent GmbH; 2021. Available at: https://www.hemovent.com/eu/solutions . Accessed February 19, 2022.
    1. Karagiannidis C, Joost T, Strassmann S, et al.: Safety and efficacy of a novel pneumatically driven extracorporeal membrane oxygenation device. Ann Thorac Surg 109: 1684–1691, 2020.
    1. Karagiannidis C, Strassmann S, Larsson A, Brodie D: The hemovent oxygenator: A new low-resistance, high-performance oxygenator. ASAIO J 67: e59–e61, 2021.
    1. Marini J: Dealing with the CARDS of COVID-19. Crit Care Med 48: 1239–1241, 2020.
    1. Badulak J, Antonini MV, Stead CM, et al.; ELSO COVID-19 Working Group Members: Extracorporeal membrane oxygenation for COVID-19: Updated 2021 guidelines from the extracorporeal life support organization. ASAIO J 67: 485–495, 2021.

MeSH terms