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Review
. 1986 Oct-Nov;16(10-11):933-55.
doi: 10.3109/00498258609038975.

The metabolism of aromatic amines

J W Gorrod, D Manson
Review

The metabolism of aromatic amines

J W Gorrod et al. Xenobiotica. 1986 Oct-Nov.

Abstract

Aromatic amines are of general interest in drug metabolism and some are a health hazard, particularly as bladder carcinogens. Conditions for the biological ring- and N-oxidation of aniline and its derivatives are reviewed. The metabolism of 2-naphthylamine and aminobiphenyls and the involvement of metabolites of aromatic amines in bladder cancer is discussed.

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