Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1986;71(3-4):341-3.
doi: 10.1007/BF00688060.

A specific histochemical marker (lectin Ricinus communis agglutinin-1) for normal human microglia, and application to routine histopathology

H Mannoji, H Yeger, L E Becker
Comparative Study

A specific histochemical marker (lectin Ricinus communis agglutinin-1) for normal human microglia, and application to routine histopathology

H Mannoji et al. Acta Neuropathol. 1986.

Abstract

Microglia were demonstrated in paraffin-embedded human nervous tissues with an avidin-biotin peroxidase method and Ricinus communis agglutinin-1 (RCA-1). Specific staining was observed in cell bodies and processes of microglia. Although endothelial cells and blood cells reacted with RCA-1, they were easily distinguished morphologically from microglia. Astrocytes, oligodendrocytes, and neurons did not react with RCA-1. These results suggest that RCA-1 can be used as a new histochemical marker for microglia in normal human brain.

PubMed Disclaimer

References

    1. Histochemistry. 1984;80(2):165-9 - PubMed
    1. J Neurocytol. 1978 Oct;7(5):601-10 - PubMed
    1. Acta Neuropathol. 1982;56(1):67-74 - PubMed
    1. J Clin Pathol. 1984 Feb;37(2):150-6 - PubMed
    1. J Pathol. 1983 Dec;141(4):435-40 - PubMed

Publication types