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Case Reports
. 2022 Mar 9;14(3):e23001.
doi: 10.7759/cureus.23001. eCollection 2022 Mar.

A Case of Complicated Pneumonia Caused by Klebsiella ozaenae

Affiliations
Case Reports

A Case of Complicated Pneumonia Caused by Klebsiella ozaenae

Takayuki Tachibana et al. Cureus. .

Abstract

Klebsiella ozaenae, a subtype of K. pneumonia, causes chronic upper respiratory tract infections, such as rhinitis and rhinoscleroma, and can also cause lethal infections. We report the case of a patient who developed pneumonia caused by K. ozaenae. An 87-year-old man presented to our hospital with fever and chills. Physical examination revealed no findings other than bilateral crackles in the lower lung fields. Chest computed tomography (CT) showed infiltrative shadows in the lower left lung field. Moreover, K. ozaenae was detected in blood cultures. Based on the examination results, including radiography and blood culture, the patient was diagnosed with pneumonia caused by K. ozaenae. On admission, the patient was treated with intravenous ceftriaxone (CTRX), but he did not recover. After determining the antibiotic susceptibility of K. ozaenae, we stopped administering CTRX and started ampicillin/sulbactam (ABPC/SBT) treatment for two weeks. During the ABPC/SBT administration, a second chest CT showed a new infiltrative shadow in the upper left lung field. Despite these findings, the patient was discharged from the hospital as his vital signs were stable and his general condition was good. After two weeks of ABPC/SBT treatment, the patient was switched to minocycline and followed up. Although infections caused by K. ozaenae are rare, they can be life-threatening. K. ozaenae identification in a patient's blood culture indicates a potentially impaired immune system, prompting physicians to evaluate the patient's immune system.

Keywords: antibiotic resistance; bacteremia; general medicine; immunocompromised; klebsiella; pneumonia; rural hospital.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Initial chest computed tomography scan showing opacity in the left lower lung zone at admission.
Figure 2
Figure 2. Second chest computed tomography scan revealing that opacity in the lower left lung lobe had improved but a new opacity had appeared in the left upper lung lobe.
Figure 3
Figure 3. Clinical course of the case.

References

    1. Klebsiella species (K. pneumoniae, K. oxytoca, K. ozaenae and K. rhinoscleromatis) [ Dec; 2021 ];Paterson DL, Siu KLK, Chang FY. http://www.antimicrobe.org/b107.asp oxytoca, K. ozaenae. 2012
    1. The effect of ethanol on the cough reflex. Berkowitz H, Reichel J, Shim C. Clin Sci Mol Med. 1973;45:527–531. - PubMed
    1. Alcohol and immune defense. MacGregor RR. JAMA. 1986;256:1474–1479. - PubMed
    1. Jain T, Sanju HK, Guerrieri M, Ralli M, Di Mauro R. Atrophic Rhinitis. Cham, Switzerland: Springer; 2020. Primary atrophic rhinitis: ozaena and other infective forms; pp. 3–9.
    1. Klebsiella ozaenae septicemia associated with Hansen's disease. Murray KA, Clements BH, Keas SE. J Clin Microbiol. 1981;14:703–705. - PMC - PubMed

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