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Comment
. 2022 Apr 15;376(6590):243-244.
doi: 10.1126/science.abp8243. Epub 2022 Apr 14.

Regulatory CD8+ T cells suppress disease

Anaïs Levescot  1 , Nadine Cerf-Bensussan  1
Affiliations
Comment

Regulatory CD8+ T cells suppress disease

Anaïs Levescot et al. Science. .

Abstract

A subset of CD8+ T cells regulate chronic inflammation by killing pathogenic CD4+ T cells.

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  • KIR+CD8+ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19.
    Li J, Zaslavsky M, Su Y, Guo J, Sikora MJ, van Unen V, Christophersen A, Chiou SH, Chen L, Li J, Ji X, Wilhelmy J, McSween AM, Palanski BA, Mallajosyula VVA, Bracey NA, Dhondalay GKR, Bhamidipati K, Pai J, Kipp LB, Dunn JE, Hauser SL, Oksenberg JR, Satpathy AT, Robinson WH, Dekker CL, Steinmetz LM, Khosla C, Utz PJ, Sollid LM, Chien YH, Heath JR, Fernandez-Becker NQ, Nadeau KC, Saligrama N, Davis MM. Li J, et al. Science. 2022 Apr 15;376(6590):eabi9591. doi: 10.1126/science.abi9591. Epub 2022 Apr 15. Science. 2022. PMID: 35258337 Free PMC article.

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