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. 1987 Feb 9;212(1):68-72.
doi: 10.1016/0014-5793(87)81558-2.

Vapor-phase modification of sulfhydryl groups in proteins

R Amons
Free article

Vapor-phase modification of sulfhydryl groups in proteins

R Amons. FEBS Lett. .
Free article

Abstract

Proteins and peptides are readily and specifically modified at their sulfhydryl groups by the vapors of a mixture of 4-vinylpyridine and tributylphosphine. The phenylthiohydantoin derivative of S-beta-(4-pyridylethyl)cysteine formed during sequence analysis is easily detectable in current identification systems.

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