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Review
. 2022 Jun;16(4):115-144.
doi: 10.1049/nbt2.12078. Epub 2022 Apr 15.

Medicinal plants mediated the green synthesis of silver nanoparticles and their biomedical applications

Haajira Beevi Habeeb Rahuman  1 , Ranjithkumar Dhandapani  1   2 , Santhoshini Narayanan  1 , Velmurugan Palanivel  3 , Ragul Paramasivam  2 , Ramalakshmi Subbarayalu  2 , Sathiamoorthi Thangavelu  1 , Saravanan Muthupandian  4   5
Affiliations
Review

Medicinal plants mediated the green synthesis of silver nanoparticles and their biomedical applications

Haajira Beevi Habeeb Rahuman et al. IET Nanobiotechnol. 2022 Jun.

Abstract

The alarming effect of antibiotic resistance prompted the search for alternative medicine to resolve the microbial resistance conflict. Over the last two decades, scientists have become increasingly interested in metallic nanoparticles to discover their new dimensions. Green nano synthesis is a rapidly expanding field of interest in nanotechnology due to its feasibility, low toxicity, eco-friendly nature, and long-term viability. Some plants have long been used in medicine because they contain a variety of bioactive compounds. Silver has long been known for its antibacterial properties. Silver nanoparticles have taken a special place among other metal nanoparticles. Silver nanotechnology has a big impact on medical applications like bio-coating, novel antimicrobial agents, and drug delivery systems. This review aims to provide a comprehensive understanding of the pharmaceutical qualities of medicinal plants, as well as a convenient guideline for plant-based silver nanoparticles and their antimicrobial activity.

Keywords: antimicrobial; eco-friendly; green synthesis; silver nanoparticles.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. There is no potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Major three disciplines of nanotechnology dry nanotechnology, wet nanotechnology, and computational nanotechnology
FIGURE 2
FIGURE 2
Two approaches of formation of metallic nanoparticles Top to bottom and Bottom to up
FIGURE 3
FIGURE 3
Synthesis of silver nanoparticles (AgNPs) using plant extract with silver nitrate (AgNO3) solution
FIGURE 4
FIGURE 4
Extracellular and intracellular synthesis of silver nanoparticles (AgNPs)
FIGURE 5
FIGURE 5
Different characterisation techniques of silver nanoparticles (AgNPs). (a) UV‐vis spectra of plant‐mediated synthesised AgNPs, silver nitrate (AgNO3), and plant extract. (b) Transmission electron microscopy (TEM) image of plant‐mediated synthesised AgNPs. (c) Selected area electron diffraction (SAED) pattern of plant‐mediated synthesised AgNPs. (d) FTIR spectra of plant‐mediated synthesised AgNPs and plant extract. (e) EDX spectra of plant‐mediated synthesised AgNPs. (f) X‐ray diffractometry (XRD) peaks of plant‐mediated synthesised AgNPs
FIGURE 6
FIGURE 6
(a) Antibacterial mechanism of plant‐mediated synthesised silver nanoparticles (AgNPs) [38] (b) Antibiofilm mechanism of plant‐mediated synthesised AgNPs [38]
FIGURE 7
FIGURE 7
(a) Antifungal mechanism of plant‐mediated synthesised silver nanoparticles (AgNPs) [115] (b) An Illustrated antiviral mechanism of plant‐mediated synthesised AgNPs
FIGURE 8
FIGURE 8
Overall view of biomedical application of silver nanoparticles (AgNPs)
See this image and copyright information in PMC

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