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. 2022 Aug 1;47(8):730-731.
doi: 10.1097/RLU.0000000000004225. Epub 2022 Apr 15.

Is Glucagon Administration Compatible With FDG PET/MRI?

Bruno Maucherat  1 , Roshanack Movassaghi  1 , Vincent Fleury  1 , Maelle Le Thiec  1 , Delphine Geffroy  1 , Catherine Labbe-Devilliers  1 , Caroline Rousseau
Affiliations

Is Glucagon Administration Compatible With FDG PET/MRI?

Bruno Maucherat et al. Clin Nucl Med. .

Abstract

Digestive peristalsis generates many artifacts that limit the abdominal and pelvic MRI interpretation. Apart from the hypoglycemia treatment in patients with diabetes, glucagon analog is also indicated for the digestive peristalsis reduction to reduce MRI artifacts. However, its use in PET/MRI is not described, given the risk of interaction with the metabolism of FDG. To assess the importance of this interaction on the FDG PET images, we report FDG PET/MRI images obtained with and without glucagon analog injection.

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Conflict of interest statement

Conflicts of interest: none declared. This work has been supported in part by grants from the French National Agency for Research called “Investissements d'Avenir” IRON Labex n° ANR-11-LABX-0018-01, EquipexArronaxPlus no. ANR-11-EQPX-0004 and from INCa-DGOS-Inserm_12558 (SIRIC ILIAD).

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