Bacteria in tumors "hit the road" together
- PMID: 35427497
- PMCID: PMC9289786
- DOI: 10.1016/j.cell.2022.03.013
Bacteria in tumors "hit the road" together
Abstract
Tumors contain bacteria, but the functional significance of this tumor microbiota is not appreciated. Fu et al. show that bacteria within breast tumor cells contribute to metastasis, in part, by enhancing tumor cell survival to mechanical fluid shear stress as would be found in the circulation.
Copyright © 2022 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The Longmore laboratory currently receives funding from Pfizer-CTI, San Diego, CA, and Centene Corporation, St. Louis, MO.
Comment on
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Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer.Cell. 2022 Apr 14;185(8):1356-1372.e26. doi: 10.1016/j.cell.2022.02.027. Epub 2022 Apr 7. Cell. 2022. PMID: 35395179
References
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