Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2022 Jul;88(7):3543-3544.
doi: 10.1111/bcp.15347. Epub 2022 Apr 15.

Analgesia and COVID-19

William F Laughey  1   2 , Imran Lodhi  1 , Olutoba Sanni  1 , Graham Pennick  1 , Bruce Charlesworth  1
Affiliations
Comment

Analgesia and COVID-19

William F Laughey et al. Br J Clin Pharmacol. 2022 Jul.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors are employees of Reckitt, the owners and distributors of the Nurofen brand.

Comment on

References

    1. Abdel Shaheed C, Beardsley J, Day RO, McLachlan AJ. Immunomodulatory effects of pharmaceutical opioids and antipyretic analgesics: Mechanisms and relevance to infection. Br J Clin Pharmacol. 2022. doi: 10.1111/bcp.15281 - DOI - PubMed
    1. Chen JS, Alfajaro MM, Wei J, et al. Cyclooxgenase‐2 is induced by SARS‐CoV‐2 infection but does not affect viral entry or replication. BioRxiv. 2020; Sep 25
    1. de Bruin N, Schneider AK, Reus P, et al. Ibuprofen, flurbiprofen, etoricoxib or paracetamol do not influence ACE2 expression and activity in vitro or in mice and do not exacerbate in‐vitro SARS‐CoV‐2 infection. Int J Mol Sci. 2022;23(3):1049. doi: 10.3390/ijms23031049 - DOI - PMC - PubMed
    1. Terrier O, Dilly S, Pizzorno A, et al. Antiviral properties of the NSAID drug naproxen targeting the nucleoprotein of SARS‐CoV‐2 coronavirus. Molecules. 2021;26(9):2593‐2609. doi: 10.3390/molecules26092593 - DOI - PMC - PubMed
    1. Saleh E, Moody MA, Walter EB. Effect of antipyretic analgesics on immune responses to vaccination. Hum Vaccin Immunother. 2016;12(9):2391‐2402. doi: 10.1080/21645515.2016.1183077 - DOI - PMC - PubMed