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Case Reports
. 2022 Mar 1;16(1):97-102.
doi: 10.1159/000521918. eCollection 2022 Jan-Apr.

Acute Pancreatitis with Colonic Pseudo-obstruction in a Patient with COVID-19

Jeremy Van  1 , Jason Kramer  2 , Ioannis Economou  2
Affiliations
Case Reports

Acute Pancreatitis with Colonic Pseudo-obstruction in a Patient with COVID-19

Jeremy Van et al. Case Rep Gastroenterol. .

Abstract

Angiotensin-converting enzyme 2 receptor, the receptor used by severe acute respiratory syndrome coronavirus-2 (COVID-19) to infect cells, is found not only on respiratory epithelium but also in the small bowel, large bowel, and pancreas. There have been rare reports of acute pancreatitis (AP) in COVID-19 patients without an obvious etiology other than the underlying viral syndrome. We present a patient who was admitted with COVID-19 and developed AP and colonic pseudo-obstruction.

Keywords: Abdominal pain; Acute pancreatitis; Intestinal obstruction.

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Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

Fig. 1
Fig. 1
a–b Abdominal radiograph (one view anterior-posterior) demonstrating a significantly dilated (9 mm diameter) gas-filled large bowel (black arrows and bars) concerning for colonic ileus.
Fig. 2
Fig. 2
a–c CT-AP without intravenous contrast (axial view) demonstrating a diffuse gas and fluid-filled dilated large bowel without definitive obstruction or transition point. d CT-AP without intravenous contrast (axial view) demonstrating a distended and fluid-filled rectum (black arrow).
Fig. 3
Fig. 3
a Abdominal radiograph (one view anterior-posterior, pre-endoscopic decompression) demonstrating multiple gas-filled dilated loops of large bowel (black arrow) and cecum (white arrow) greater than 10 mm dilation. b Abdominal radiograph (one view anterior-posterior, post-endoscopic decompression) demonstrating no dilation of large bowel.
See this image and copyright information in PMC

References

    1. Johns Hopkins University of Medicine Coronavirus Resource Center Website Available from: https://coronavirus.jhu.edu. Accessed 2021 Mar 24.
    1. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020 Feb;395((10223)):497–506. - PMC - PubMed
    1. Zhou Z, Zhao N, Shu Y, Han S, Chen B, Shu X. Effect of Gastrointestinal symptoms in patients with COVID-19. Gastroenterology. 2020 Jun;158((8)):2294–2297. - PMC - PubMed
    1. Holshue ML, DeBolt C, Lindquist S, Lofy KH, Wiesman J, Bruce H, et al. First case of 2019 novel coronavirus in the United States. N Engl J Med. 2020 Mar;382((10)):929–936. - PMC - PubMed
    1. Lamers MM, Beumer J, van der Vaart J, Knoops K, Puschhof J, Breugem TI, et al. SARS-CoV-2 productively infects human gut enterocytes. Science. 2020 Jul;369((6499)):50–4. - PMC - PubMed

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