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Clinical Trial
. 1986 Dec;100(12):1347-50.
doi: 10.1017/s0022215100101124.

Efficacy of medical treatment as an adjunct to surgery in the treatment of secretory otitis media

Clinical Trial

Efficacy of medical treatment as an adjunct to surgery in the treatment of secretory otitis media

T H Lesser et al. J Laryngol Otol. 1986 Dec.

Abstract

In a pilot controlled randomised trial of 38 children who had bilateral secretory otitis media, with effusion demonstrated at operation, we compared the efficacy of a six-week course of an oral decongestant--antihistamine combination and a mucolytic preparation with a control group in preventing the presence of middle-ear effusion six weeks after myringotomy and adenoidectomy. The mucolytic preparation decreased the presence of middle-ear effusion when compared to the decongestant-antihistamine combination and the control group (p = 0.06).

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