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Review
. 2022 Mar 30:13:807632.
doi: 10.3389/fphys.2022.807632. eCollection 2022.

Pancreas-Its Functions, Disorders, and Physiological Impact on the Mammals' Organism

Affiliations
Review

Pancreas-Its Functions, Disorders, and Physiological Impact on the Mammals' Organism

Monika Karpińska et al. Front Physiol. .

Abstract

This review aimed to analyze the scientific literature on pancreatic diseases (especially exocrine pancreatic insufficiency). This review also describes the correlation between the physiological fitness of the pancreas and obesity. The influence of the pancreatic exocrine function on the development of the organism of adults and adolescents was also described. The results of piglet studies available in the literature were cited as an established model used to optimize treatments for pancreatic diseases in humans. The pancreas has an exocrine and hormonal function. Consequently, it is one of the key internal organs in animals and humans. Pancreatic diseases are usually severe and particularly troublesome. A properly composed diet and taken dietary supplements significantly improve the patient's well-being, as well as the course of the disease. Therefore, a diet and a healthy lifestyle positively affect maintaining the optimal physiological efficiency of the pancreas.

Keywords: diabetes; obesity; pancreas; pancreatic disorders; pancreatic exocrine insufficiency (EPI).

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
General diagram of the human pancreas (shutterstock).

References

    1. Adler G., Kern H. F. (1975). Regulation of exocrine pancreatic secretory process by insulin. Horm. Metab. Res. 7 290–296. 10.1055/s-0028-1093717 - DOI - PubMed
    1. Ahima R. S. (2011). Digging deeper into obesity. J. Clin. Invest. 121 2076–2079. 10.1172/JCI58719 - DOI - PMC - PubMed
    1. Al-Husseina A.-B. A., Tahira F. R., Pham V. T. (2021). Fixed-time synergetic control for chaos suppression in endocrine glucose–insulin regulatory system. Control Eng. Pract. 108:104723. 10.1016/j.conengprac.2020.104723 - DOI
    1. American Cancer Society Cancer (2021). Prevention Study II (CPS-II). Available online at: https://www.cancer.org/research/we-conduct-cancer-research/behavioral-an... (accessed April 15, 2021)
    1. Bang U. C., Benfield T., Bendtsen F., Hildstrup L., Beck Jensen J. E. (2014a). The risk of fractures among patients with cirrhosis or chronic pancreatitis. Clin. Gastroenterol. Hepatol. 12 320–326. 10.1016/j.cgh.2013.04.031 - DOI - PubMed

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