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. 2021 Sep 17;13(1):1-13.
doi: 10.1108/MIJ-05-2021-0002. eCollection 2021.

The use of repetitive transcranial magnetic stimulation for treatment of obsessive-compulsive disorder: a scoping review

Medard Kofi Adu  1 , Ejemai Eboreime  1 , Adegboyega Oyekunbi Sapara  1 , Andrew James Greenshaw  1 , Pierre Chue  1 , Vincent Israel Opoku Agyapong  1
Affiliations

The use of repetitive transcranial magnetic stimulation for treatment of obsessive-compulsive disorder: a scoping review

Medard Kofi Adu et al. Ment Illn. .

Abstract

Purpose: This paper aims to explore the relevant literature available regarding the use of repetitive transcranial magnetic stimulation (rTMS) as a mode of treatment for obsessive-compulsive disorder (OCD); to evaluate the evidence to support the use of rTMS as a treatment option for OCD.

Design/methodology/approach: The authors electronically conducted data search in five research databases (MEDLINE, CINAHL, Psych INFO, SCOPUS and EMBASE) using all identified keywords and index terms across all the databases to identify empirical studies and randomized controlled trials. The authors included articles published with randomized control designs, which aimed at the treatment of OCD with rTMS. Only full-text published articles written in English were reviewed. Review articles on treatment for conditions other than OCD were excluded. The Covidence software was used to manage and streamline the review.

Findings: Despite the inconsistencies in the published literature, the application of rTMS over the supplementary motor area and the orbitofrontal cortex has proven to be promising in efficacy and tolerability compared with other target regions such as the prefrontal cortex for the treatment of OCD. Despite the diversity in terms of the outcomes and clinical variability of the studies under review, rTMS appears to be a promising treatment intervention for OCD.

Research limitations/implications: The authors of this scoping review acknowledge several limitations. First, the search strategy considered only studies published in English and the results are up to date as the last day of the electronic data search of December 10, 2020. Though every effort was made to identify all relevant studies for the purposes of this review per the eligibility criteria, the authors still may have missed some relevant studies, especially those published in other languages.

Originality/value: This review brought to bare the varying literature on the application of rTMS and what is considered gaps in the knowledge in this area in an attempt to evaluate and provide information on the potential therapeutic effects of rTMS for OCD.

Keywords: Bipolar disorders; Obsessive-compulsive disorder; Post-traumatic stress disorder; Repetitive transcranial magnetic stimulations; Treatment.

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Figures

Figure 1
Figure 1
Prisma flow diagram summarizing search process and results
Figure 2
Figure 2
Number of studies extracted from the various continents (n = 28)
See this image and copyright information in PMC

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References

    1. Arumugham, Shyam Sundar MD, VS, Subhasini DN, HN, Madhuri DPM, B, Vinay MD, Ravi, Malvika MD, Sharma, Eesha MD, Thirthalli, Jagadisha MD, Reddy and YC Janardhan MD (2018), “Augmentation effect of Low-Frequency repetitive transcranial magnetic stimulation over presupplementary motor area in Obsessive-Compulsive disorder: a randomized controlled trial”, The Journal of Ect, Vol. 34 No. 4, pp. 253-257. - PubMed
    1. Badawy, A.A., Sawy, H.E. and Hay, M.E. (2010), “Efficacy of repetitive transcranial magnetic stimulation in the management of obsessive compulsive disorder”, Egyptian Journal of Neurology, Psychiatry and Neurosurgery, Vol. 47, pp. 393-397.
    1. Barker, A.T., Jalinous, R. and Freeston, I.L. (1985), “Non-invasive magnetic stimulation of human motor cortex”, The Lancet, Vol. 325 No. 8437, pp. 1106-1107. - PubMed
    1. Blumberger, Daniel M., Mulsant, Benoit H., Fitzgerald, Paul B., Rajji, Tarek K., Ravindran, Arun V., Young, Trevor L., Levinson, Andrea J. and Daskalakis Zafiris J. (2012), “A randomized double-blind sham-controlled comparison of unilateral and bilateral repetitive transcranial magnetic stimulation for treatment-resistant major depression”, The World Journal of Biological Psychiatry, Vol. 13 No. 6, pp. 423-435. - PubMed
    1. Burt, T., Lisanby, S.H. and Sackeim, H.A. (2002), “Neuropsychiatric applications of transcranial magnetic stimulation: a Meta analysis”, International Journal of Neuropsychopharmacology, Vol. 5 No. 1, pp. 73-103. - PubMed

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