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. 2022 Apr 7:2022:9185384.
doi: 10.1155/2022/9185384. eCollection 2022.

Effects of Acupuncture and Moxibustion Combined with Needle-Knife on Pain and Lumbar Function in Patients with Lumbar Disc Herniation

Guoqiang Peng  1 , Yanfang Zheng  2 , Dejun Luo  3
Affiliations

Effects of Acupuncture and Moxibustion Combined with Needle-Knife on Pain and Lumbar Function in Patients with Lumbar Disc Herniation

Guoqiang Peng et al. J Healthc Eng. .

Retraction in

Abstract

This study aimed for the analysis of the effect of acupuncture and moxibustion combined with needle-knife on pain and lumbar function in patients with lumbar disc herniation. From June 2019 to February 2021, the medical records of 126 patients with lumbar disc herniation admitted to the department of orthopedics of our hospital were selected and divided into the control group (n = 63) treated with acupuncture and moxibustion and the observation group (n = 63) treated with acupuncture and moxibustion combined with needle-knife according to different treatment regimens. After 4 weeks of treatment, the clinical efficacy, pain status, and lumbar function were compared between the two groups. The concentrations of relevant inflammatory factors (IL-6, IL-10, TNF-α, and MMP-2) in peripheral blood of the two patients before and after treatment were measured by enzyme-linked immunosorbent assay (ELISA). After treatment, the overall response rate was 93.65% in the observation group, which was higher than 80.95% in the control group (P < 0.05); the visual blurred score (VAS) scores of lower limbs and waist in the observation group were lower than those in the control group, while the expression of pain mediators serotonin (5-HT) and prostaglandin E2 (PEG2) was also lower than that in the control group (P < 0.05); the Oswestry disability index (ODI) in the observation group was lower than that in the control group, while the Japanese Orthopedic Association assessment treatment score (JOA) was higher than that in the control group (P < 0.05). After treatment, the concentration levels in peripheral blood (IL-6, IL-10, TNF-α, and MMP-2) were significantly lower in the observation group than in the control group (P < 0.05). Acupuncture and moxibustion combined with needle-knife is effective in the treatment of lumbar disc herniation, which helps to improve the clinical efficacy, relieve pain symptoms, promote the improvement of lumbar function, and contribute to the reduction of inflammatory factors.

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Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

Figure 1
Figure 1
The changes of IL-6 concentrations changes in peripheral blood detected by ELISA in two groups before and after treatment (x̅ ± s). ∗P < 0.05, compared with the control group.
Figure 2
Figure 2
The changes of IL-10 concentrations changes in peripheral blood detected by ELISA in two groups before and after treatment (x̅ ± s). ∗P < 0.05, compared with the control group.
Figure 3
Figure 3
The changes of TNF-α concentrations changes in peripheral blood detected by ELISA in two groups before and after treatment (x̅ ± s). ∗P < 0.05, compared with the control group.
Figure 4
Figure 4
The changes of MMP-2 concentrations changes in peripheral blood detected by ELISA in two groups before and after treatment (x̅ ± s). ∗P < 0.05, compared with the control group.
See this image and copyright information in PMC

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