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Review
. 2022 Apr 8:2022:1568406.
doi: 10.1155/2022/1568406. eCollection 2022.

Application of Intraoperative Optical Coherence Tomography Technology in Anterior Segment Surgery

Sang Beom Han  1 , Yu-Chi Liu  2   3   4 , Karim Mohamed-Noriega  5 , Jodhbir S Mehta  2   3   4
Affiliations
Review

Application of Intraoperative Optical Coherence Tomography Technology in Anterior Segment Surgery

Sang Beom Han et al. J Ophthalmol. .

Abstract

The use of optical coherence tomography (OCT) technology in anterior segment diseases allows for precise assessment of the changes following anterior segment surgery. Advances in microscope-integrated OCT systems have allowed the utilization of intraoperative OCT (iOCT) in anterior segment surgeries, i.e., cornea, cataract, and refractive surgery. iOCT has enabled real-time precise visualization of anterior segment tissues as well as interactions between surgical instruments and ocular tissue; thus, the device can facilitate surgical procedures and provide valuable information for decision-making during anterior segment surgeries. In this review, the authors will introduce studies regarding the development of iOCT technology and its application in various anterior segment surgeries. Multiple studies have shown the efficacy of the iOCT for intraoperative assistance and guidance, suggesting the potential of the device for optimizing the surgical outcomes after cornea, cataract, and refractive surgery.

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Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

Figure 1
Figure 1
Display of an image of the intraoperative optical coherence tomography (iOCT) integrated into the microscope during the cataract surgery.
Figure 2
Figure 2
Application of the iOCT in DALK surgery. (a) Visualization of the residual stromal bed. (b) Confirmation of the attachment between the graft cornea and recipient bed (c) visualization of the tissue underneath the cloudy cornea using the iOCT during the viscodissection.
Figure 3
Figure 3
Application of the iOCT in DSAEK and DMEK surgery. (a) Confirmation of the attachment of the endothelial graft during DMEK. (b) Visualization of the detached endothelial graft cornea in DMEK. (c) Visualization of the peripheral anterior synechiae during DSAEK. (d) Visualization of the donor fold before donor graft insertion in DMEK.
See this image and copyright information in PMC

References

    1. Price F. W., Jr. Intraoperative optical coherence tomography: game-changing technology. Cornea . 2021;40(6):675–678. doi: 10.1097/ico.0000000000002629. - DOI - PubMed
    1. Ehlers J. P. Intraoperative optical coherence tomography: past, present, and future. Eye . 2016;30(2):193–201. doi: 10.1038/eye.2015.255. - DOI - PMC - PubMed
    1. Han S. B., Mehta J. S., Liu Y. C., Mohamed-Noriega K. Advances and clinical applications of anterior segment imaging techniques. Journal of ophthalmology . 2016;2016:2. doi: 10.1155/2016/8529406.8529406 - DOI - PMC - PubMed
    1. Meduri A., Bergandi L., Perroni P., Silvagno F., Aragona P. Oral l-cysteine supplementation enhances the long term-effect of topical basic fibroblast growth factor (bFGF) in reducing the corneal haze after photorefractive keratectomy in myopic patients. Pharmaceuticals . 2020;13(4) doi: 10.3390/ph13040067. - DOI - PMC - PubMed
    1. Muijzer M. B., Schellekens P., Beckers H. J. M., de Boer J. H., Imhof S. M., Wisse R. P. Clinical applications for intraoperative optical coherence tomography: a systematic review. Eye . 2022;36(2):379–391. doi: 10.1038/s41433-021-01686-9. - DOI - PMC - PubMed

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