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. 2022 Mar 16;12(1):e121809.
doi: 10.5812/aapm.121809. eCollection 2022 Feb.

Evaluation of the Relationship Between Changes in Potassium Concentration and Arrhythmia During Coronary Artery Bypass Grafting Surgery

Sara Jorairahmadi  1 , Fatemeh Javaherforooshzadeh  1 , Farahzad Jannatmakan  1 , Farhad Soltani  1 , Liah Shidel Zadeh  1
Affiliations

Evaluation of the Relationship Between Changes in Potassium Concentration and Arrhythmia During Coronary Artery Bypass Grafting Surgery

Sara Jorairahmadi et al. Anesth Pain Med. .

Abstract

Background: Coronary artery bypass grafting (CABG) surgery is a treatment option for coronary artery diseases. Cardiac arrhythmias during CABG surgery can lead to serious complications. Potassium ion concentration is a factor involved in such arrhythmias.

Objectives: This study aimed to investigate the relationship between potassium concentration and cardiac arrhythmias in CABG surgery.

Methods: This descriptive cross-sectional study was performed on 60 patients with the American Society of Anesthesiologists class I, II, and III undergoing CABG surgery at Golestan Hospital, Ahvaz, Iran. All patients underwent general anesthesia, and ventilator control was achieved by mechanical ventilation. The on-pump method was used for CABG. Potassium levels were measured at several time points during surgery. All cardiac arrhythmias were recorded. Mean arterial pressure (MAP), serum level of potassium, blood sugar, blood urea nitrogen (BUN), creatinine, calcium, magnesium, hemoglobin (Hb), and sodium were also recorded.

Results: The mean age of the patients was 60.87 ± 7.35 years, and 45% of the subjects were female. Moreover, there was no statistically significant difference between the patients. There was a significant relationship between the changes in MAP, potassium, blood sugar, BUN, creatinine, calcium, and magnesium with the incidence of cardiac arrhythmias (P < 0.05). However, no significant relationship was noted between Hb and sodium levels with the incidence of cardiac arrhythmias (P < 0.05).

Conclusions: The changes in potassium levels increase the risk of cardiac arrhythmias and their complications.

Keywords: Cardiac Arrhythmias; Coronary Artery Bypass Grafting; Hyperkalemia; Hypokalemia; Sodium.

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Conflict of interest statement

Conflict of Interests: The authors report no conflicts of interest. The authors alone are responsible for content and writing of this article.

Figures

Figure 1.
Figure 1.. (A) Changes in mean arterial pressure (MAP) in arrhythmic group (n = 27) and nonarrhythmic group (n = 33) before the operation, after induction, on pump, after pump, and on entering to intensive care unit measurements (P = 0.082; repeated measures analysis of variance [ANOVA]); (B) Changes in blood urea nitrogen in arrhythmic group (n = 27) and nonarrhythmic group (n = 33) (P < 0.005; repeated measures ANOVA); (C) Changes in creatinine clearance (P = 0.519; repeated measures ANOVA); (D) Changes in hemoglobin (P = 0.486; repeated measures ANOVA); (E) Changes in blood potassium level (P < 0.001; repeated measures ANOVA); (F) Changes in blood sodium level (P > 0.0.5; repeated measures ANOVA); (G) Changes in blood sugar level (P > 0.0.5; repeated measures ANOVA); (H) Changes in blood calcium level (P > 0.0.5; repeated measures ANOVA); (I) Changes in blood magnesium level (P > 0.0.5; repeated measures ANOVA)
See this image and copyright information in PMC

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