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. 2022 Oct;65(1):103-110.
doi: 10.1007/s10840-022-01208-x. Epub 2022 Apr 18.

Performance of transcatheter pacing system use in relation to patients' age

Antonino Nicosia  1 , Saverio Iacopino  2 , Gerardo Nigro  3 , Giulio Zucchelli  4 , Luca Tomasi  5 , Carlo D'Agostino  6 , Matteo Ziacchi  7 , Marcello Piacenti  8 , Paolo De Filippo  9 , Giuseppe Sgarito  10 , Giuseppe Campisi  11 , Daniele Nicolis  12 , Rosario Foti  13 , Pietro Palmisano  14
Affiliations

Performance of transcatheter pacing system use in relation to patients' age

Antonino Nicosia et al. J Interv Card Electrophysiol. 2022 Oct.

Abstract

Purpose: Real-world safety data on the use of transcatheter pacing systems particularly in very elderly patients is still limited. The aim of this analysis was to investigate the effect of age on the safety and efficacy of leadless pacemaker implant.

Methods: From May 2016 through July 2019, 577 patients were implanted with a leadless single-chamber pacemaker according to current pacing indication in 15 Italian cardiologic centers. The population was divided into age quartiles for evaluation, including (1) < 70 years, (2) 70-77 years, (3) 78-83 years, and (4) ≥ 83 years. Procedural data, complications, and electrical parameters were collected at baseline and during the follow-up.

Results: Procedural-related complication occurrence was very low (< 1.0%) and similar in the four subgroups according to age even if the older patients were more frail. No cardiac tamponade was reported. Among the groups, no difference was observed in procedural time, fluoroscopy time duration, and electrical parameters (mean pacing impedance: 750 ± 192 and 599 ± 156, mean pacing threshold: 0.7 ± 0.5 and 0.7 ± 0.6, and mean right ventricular sensing 10.7 ± 6.1 and 11.5 ± 4.8 at implant and last follow-up, respectively).

Conclusions: The reported data demonstrated a high degree of safety during leadless implant across all patient ages. Procedural complications and device electrical measurements were similar among the different ages.

Keywords: Age; Complication; Leadless pacemaker; Transcatheter pacing system.

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