Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Multicenter Study
. 2022 Jun;57(6):1042-1044.
doi: 10.1038/s41409-022-01676-9. Epub 2022 Apr 19.

Deciphering the effects of graft Tregs on chronic graft-versus-host disease: results from a prospective, multicenter study in patients with acute leukemia undergoing allogeneic peripheral blood stem cell transplantation

Mario Delia  1 , Paola Carluccio  2 , Vito Pier Gagliardi  2 , Anna Mestice  2   3 , Patrizia Chiusolo  4 , Mario Arpinati  5 , Giulio Antonio Milone  6 , Massimo Martino  7 , Patrizio Mazza  8 , Claudia Ingrosso  8 , Adriana Vacca  9 , Giorgia Saporiti  10 , Francesco Zallio  11 , Immacolata Attolico  2 , Domenico Pastore  12 , Giorgina Specchia  13 , Francesco Albano  2   3 , Pellegrino Musto  2   3
Affiliations
Multicenter Study

Deciphering the effects of graft Tregs on chronic graft-versus-host disease: results from a prospective, multicenter study in patients with acute leukemia undergoing allogeneic peripheral blood stem cell transplantation

Mario Delia et al. Bone Marrow Transplant. 2022 Jun.
No abstract available

PubMed Disclaimer

References

    1. Jagasia M, Arora M, Flowers MED, Chao NJ, McCarthy PL, Cutler CS, et al. Risk factors for acute GVHD and survival after hematopoietic cell transplantation. Blood. 2012;119:296–397. - DOI
    1. Wolf D, Wolf AM, Fong D, Rumpold H, Strasak A, Clausen J, et al. Regulatory T-cells in the graft and the risk of acute graft-versus-host disease after allogeneic stem cell transplantation. Transplantation. 2007;83:1107–13. - DOI
    1. Pabst C, Schirutschke H, Ehninger G, Bornhäuser M, Platzbecker U. The graft content of donor T cells expressing TCR+ and CD4+foxp3+ predicts the risk of acute graft-versus-host disease after transplantation of allogeneic peripheral blood stem cells from unrelated donors. Clin Cancer Res. 2007;13:2916–22. - DOI
    1. Clark FJ, Gregg R, Piper K, Dunnion D, Freeman L, Griffiths M, et al. Chronic graft-versus-host disease is associated with increased numbers of peripheral blood CD4+CD25high regulatory T cells. Blood. 2004;103:2410–16. - DOI
    1. Ukena SN, Grosse J, Mischak-Weissinger E, Buchholz S, Stadler M, Ganser A, et al. Acute but not chronic graftversus-host disease is associated with a reduction of circulating CD4+CD25highCD127low regulatory T cells. Ann Hematol. 2011;90:213–18. - DOI

MeSH terms

LinkOut - more resources