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. 2022 Oct;89(10):1028-1030.
doi: 10.1007/s12098-022-04165-5. Epub 2022 Apr 20.

Retinopathy of Prematurity and Possible Relation Between Postnatal Cytomegalovirus Infection

Maria Josa  1 , María José García  1 , Esther López  1 , Teresa Marieges  2 , Miquel Ramón  1 , Laura Armendariz  1 , Elisenda Moliner  3
Affiliations

Retinopathy of Prematurity and Possible Relation Between Postnatal Cytomegalovirus Infection

Maria Josa et al. Indian J Pediatr. 2022 Oct.

Abstract

Retinopathy of prematurity (ROP) is an eye disorder characterized by abnormal development of retinal blood vessels in premature infants. It has been associated with several risk factors, but the main factor is gestational age. Several studies have recently reported a possible link between ROP and postnatal cytomegalovirus (CMV) infection. The authors present 4 patients who developed severe ROP following postnatal CMV infection. ROP was successfully resolved with antiviral treatment in all 4 cases. Postnatal CMV infection could be responsible for the worsening of ROP. Antiviral therapy may improve the prognosis of ROP and avoid the need for more aggressive therapies.

Keywords: Cytomegalovirus infection; Prematurity; Retinopathy.

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