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Review
. 2022 Apr 22;8(16):eabq2807.
doi: 10.1126/sciadv.abq2807. Epub 2022 Apr 20.

Toward more streamlined testing in pediatric oncology

Michael F Walsh  1
Affiliations
Review

Toward more streamlined testing in pediatric oncology

Michael F Walsh. Sci Adv. .

Abstract

Gene sequencing of blood plasma simultaneously detects cancer and infectious disease in pediatric leukemia patients.

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Figures

Fig. 1.
Fig. 1.. Tandem genome sequencing detects residual leukemia and viral pathogens in cfDNA.
A custom blood test showing genetic disease variants and infection, the two factors implicated in negative prognosis, could reduce the number of invasive bone marrow biopsies and aspirations pediatric leukemia patients may be required to undergo. ctDNA, circulating tumor DNA. cfDNA, cell-free DNA. Credit: Ashley Mastin/Science Advances.
See this image and copyright information in PMC

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