Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2022 Jul 1;206(1):10-12.
doi: 10.1164/rccm.202203-0432ED.

Mycobacterium tuberculosis: A Pathogen That Can Hold Its Breath a Long Time

Affiliations
Editorial

Mycobacterium tuberculosis: A Pathogen That Can Hold Its Breath a Long Time

Moagi T Shaku et al. Am J Respir Crit Care Med. .
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
A sealed culture of Mycobacterium tuberculosis inoculated on April 4, 1920, and held at 37°C until the spring of 1932. Cultures from the sediments of this bottle grew viable M. tuberculosis, which was shown to be virulent in guinea pigs. Reprinted from Reference .

Comment on

Similar articles

Cited by

References

    1. Bucşan AN, Veatch A, Singh DK, Akter S, Golden NA, Kirkpatrick M, et al. Response to hypoxia and the ensuing dysregulation of inflammation impacts Mycobacterium tuberculosis pathogenicity. Am J Respir Crit Care Med . 2022;206:94–104. - PMC - PubMed
    1. Sherman DR, Voskuil M, Schnappinger D, Liao R, Harrell MI, Schoolnik GK. Regulation of the Mycobacterium tuberculosis hypoxic response gene encoding α-crystallin. Proc Natl Acad Sci U S A . 2001;98:7534–7539. - PMC - PubMed
    1. Mehra S, Foreman TW, Didier PJ, Ahsan MH, Hudock TA, Kissee R, et al. The DosR regulon modulates adaptive immunity and is essential for Mycobacterium tuberculosis persistence. Am J Respir Crit Care Med . 2015;191:1185–1196. - PMC - PubMed
    1. Ramakrishnan L. Revisiting the role of the granuloma in tuberculosis. Nat Rev Immunol . 2012;12:352–366. - PubMed
    1. Rustad TR, Sherrid AM, Minch KJ, Sherman DR. Hypoxia: a window into Mycobacterium tuberculosis latency. Cell Microbiol . 2009;11:1151–1159. - PubMed

Substances