Paraganglioma in pregnancy: A case series and literature review
- PMID: 35444717
- PMCID: PMC9014550
- DOI: 10.1177/1753495X211006012
Paraganglioma in pregnancy: A case series and literature review
Abstract
Paragangliomas are rare neuroendocrine neoplasms which are often catecholamine-secreting and associated with familial syndromes. Described here are three women with a variety of pathology: isolated secretory paraganglioma diagnosed in pregnancy, secretory metastatic paraganglioma in pregnancy and non-secretory metastatic paraganglioma in pregnancy. Whilst paragangliomas are associated with morbidity and mortality during pregnancy, good maternal and fetal outcomes can be achieved through individualised care within the context of a multidisciplinary team. Although paragangliomas are associated with morbidity and mortality in pregnancy, good maternal and fetal outcomes can be achieved through individualised care within the context of a multidisciplinary team.
Keywords: Paraganglioma; catecholamines; hypertension; pregnancy outcomes.
© The Author(s) 2021.
Conflict of interest statement
Declaration of conflicting interests: The author(s) declare no potential conflicts of interest with respect to research, authorship and/or publication of this article.
References
-
- Lenders JWM, Duh Q-Y, Eisenhofer G, et al.. Pheochromocytoma and paraganglioma: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 2014; 99: 1915–1942. - PubMed
-
- Amar L, Bertherat J, Baudin E, et al.. Genetic testing in pheochromocytoma or functional paraganglioma. J Clin Oncol 2005; 23: 8812–8818. - PubMed
-
- Erlic Z, Neumann HP. When should genetic testing be obtained in a patient with phaeochromocytoma or paraganglioma? Clin Endocrinol (Oxf) 2009; 70: 354–357. - PubMed
-
- Joynt KE, Moslehi JJ, Baughman KL. Paragangliomas: etiology, presentation, and management. Cardiol Rev 2009; 17: 159–164. - PubMed
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