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Case Reports
. 2021 Oct-Dec;47(4):602-607.
doi: 10.12865/CHSJ.47.04.19. Epub 2021 Dec 31.

Vulvar Verrucous Carcinoma and Genital Condylomatosis

Alina Maria Vîlcea  1 , Loredana Elena Stoica  1 , Nicolae Cernea  2 , Marius Cristian Marinaş  2 , Tiberiu Ştefăniţă Ţenea-Cojan  3
Affiliations
Case Reports

Vulvar Verrucous Carcinoma and Genital Condylomatosis

Alina Maria Vîlcea et al. Curr Health Sci J. 2021 Oct-Dec.

Abstract

Verrucous carcinoma is a histopathological type of well-differentiated squamous cell carcinoma, clinically characterized by slow and continuous growth, having a local destructive character, but low metastasis potential. Condyloma acuminatum is a sexually transmitted infection caused mainly by subtypes 6 and 11 of HPV, with subtypes 16, 18 being involved in malignant transformation. We present the case of a 70-year-old woman, hospitalized for a vulvar and perineal vegetative, ulcerated, bleeding tumor, with onset 20 years ago. The therapeutic option was surgical excision of the lesions and long-term oncological monitoring.

Keywords: Buschke-Löwenstein tumor; HPV; Verrucous vulvar carcinoma; condyloma acuminatum.

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Conflict of interest statement

None to declare.

Figures

Figure 1
Figure 1
Vegetative, verrucous tumor cauliflower-like located at the level of the right labia majora and the posterior vulvar commissure; B. Vulvar verrucous carcinoma and perineal pedunculated tumor with the keratotic surface
Figure 2
Figure 2
Postoperative dehiscence with purulent discharge; B. Dehiscence wound with granulation tissue, aspect at discharge
Figure 3
Figure 3
Right major labia tumor-well-differentiated squamous cell carcinoma, invasively in muscular tissue, H&E stain ×20; B. Verrucous carcinoma, H&E stain ×20; C. Posterior commissure tumor-papillomatosis, acanthosis, koilocytosis, hyperkeratosis and low-grade dysplasia H&E stain ×20; D. Perineal tumor-squamous epithelium with koilocytosis, H&E stain ×100
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