Doxycycline for bleeding in hereditary hemorrhagic telangiectasia: When low-hanging fruit meets inconvenient data
- PMID: 35445574
- DOI: 10.1111/jth.15675
Doxycycline for bleeding in hereditary hemorrhagic telangiectasia: When low-hanging fruit meets inconvenient data
Comment on
-
North American Study for the Treatment of Recurrent Epistaxis with Doxycycline: The NOSTRIL trial.J Thromb Haemost. 2022 May;20(5):1115-1125. doi: 10.1111/jth.15662. Epub 2022 Feb 17. J Thromb Haemost. 2022. PMID: 35108451 Clinical Trial.
References
REFERENCES
-
- Ogut D, Reel B, Gonen Korkmaz C, Arun MZ, Cilaker Micili S, Ergur BU. Doxycycline down-regulates matrix metalloproteinase expression and inhibits NF-kappaB signaling in LPS-induced PC3 cells. Folia Histochem Cytobiol. 2016;54:171-180. doi:10.5603/FHC.a2016.0022
-
- Jordan AC, Meek JC, Kanaan A, Lensing S, Meek M. Novel pharmacological therapy for the treatment of epistaxis in patients with hereditary hemorrhagic telangiectasia. J Vasc Interv Radiol. 2015;26:S114.
-
- Gaillard S, Dupuis-Girod S, Boutitie F, et al. Tranexamic acid for epistaxis in hereditary hemorrhagic telangiectasia patients: a European cross-over controlled trial in a rare disease. J Thromb Haemost. 2014;12:1494-1502. doi:10.1111/jth.12654
-
- Geisthoff UW, Seyfert UT, Kubler M, Bieg B, Plinkert PK, Konig J. Treatment of epistaxis in hereditary hemorrhagic telangiectasia with tranexamic acid - a double-blind placebo-controlled cross-over phase IIIB study. Thromb Res. 2014;134:565-571. doi:10.1016/j.thromres.2014.06.012
-
- Faughnan ME, Mager JJ, Hetts SW, et al. Second international guidelines for the diagnosis and management of hereditary hemorrhagic telangiectasia. Ann Intern Med. 2020;173:989-1001. doi:10.7326/M20-1443
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources