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Comment
. 2022 Apr 20;110(8):1277-1280.
doi: 10.1016/j.neuron.2022.03.012.

CLP1-dependent premature transcription termination opposes neurodegeneration

Michal R Gdula  1 , Magda Kopczyńska  2 , Upasana Saha  2 , Kinga Kamieniarz-Gdula  3
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CLP1-dependent premature transcription termination opposes neurodegeneration

Michal R Gdula et al. Neuron. .
Free article

Abstract

Usage of alternative mRNA 3' ends has profound functional consequences, particularly in the nervous system. In this issue of Neuron, LaForce et al. (2022) dissect the effect of CLP1 on mRNA 3' end diversity in motor neuron models of neurodegeneration.

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Declaration of interests The authors declare no competing interests.

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