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Case Reports
. 2022 Jul;85(1):e15-e17.
doi: 10.1016/j.jinf.2022.04.023. Epub 2022 Apr 18.

A case of breakthrough infection with SARS-CoV-2 Delta derivative and reinfection with Omicron variant in a fully vaccinated health care professional

Affiliations
Case Reports

A case of breakthrough infection with SARS-CoV-2 Delta derivative and reinfection with Omicron variant in a fully vaccinated health care professional

Priyanka Pandit et al. J Infect. 2022 Jul.
No abstract available

Keywords: Breakthrough; COVID-19; Delta; Omicron; Reinfection.

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Conflict of interest statement

Conflicts of Interest Authors do not have a conflict of interest among themselves.

Figures

Fig 1
Fig. 1
Timeline of the first, second and third infection: The clinical presentation of the three episodes, vaccination schedule and GISAID accession IDs of the two sequences are depicted.
Fig 2
Fig. 2
(A) MEGA-7 software was used to construct a neighbor-joining tree using a Tamura 3-parameter model with gamma distribution (0.5) and a bootstrap replication of 1000 cycles. The reference sequences of SARS-CoV-2 VOCs are shown along with the sequences obtained from specimens collected during breakthrough infection (EPI_ISL_11208201) marked with green color and Reinfection (EPI_ISL_11211347) marked with brown color. (B) Single nucleotide variation in the ORF 1a, ORF1 b, S, ORF 3a, E, M, ORF 6, ORF7ab, ORF 8 and N genes and its frequency in the two sequences of Breakthrough (EPI_ISL_11208201) and Reinfection (EPI_ISL_11211347). The X-axis is the SNVs and Y-axis represents the frequency.

Comment on

  • Disease severity during SARS-COV-2 reinfection: a nationwide study.
    Mensah AA, Lacy J, Stowe J, Seghezzo G, Sachdeva R, Simmons R, Bukasa A, O'Boyle S, Andrews N, Ramsay M, Campbell H, Brown K. Mensah AA, et al. J Infect. 2022 Apr;84(4):542-550. doi: 10.1016/j.jinf.2022.01.012. Epub 2022 Jan 25. J Infect. 2022. PMID: 35085659 Free PMC article.

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