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Review
. 2022 Apr 15:15:4079-4090.
doi: 10.2147/IJGM.S295859. eCollection 2022.

HIV-Associated Neurocognitive Disorder (HAND): Obstacles to Early Neuropsychological Diagnosis

Affiliations
Review

HIV-Associated Neurocognitive Disorder (HAND): Obstacles to Early Neuropsychological Diagnosis

Zsolt Vastag et al. Int J Gen Med. .

Abstract

Despite the recent advances in HIV treatment, HIV-associated neurocognitive disorder (HAND) prevalence remains high, especially in the mild forms. Current recommendations endorse routine screening for HAND and early identification, but there are several obstacles in diagnosing and managing cognitive impairment in people living with HIV. The purpose of this review is to provide an overview of the concepts and diagnostic tools in the field of HAND and report on the strengths and limitations of currently available approaches.

Keywords: HIV infection; cognitive disorders; cognitive test; neuropsychology; screening.

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Conflict of interest statement

The authors report no conflicts of interest in this work.

References

    1. UNAIDS. Global AIDS Update. Joint United Nations Programme on HIV/AIDS 26 February 2022. Available from: https://www.unaids.org/sites/default/files/media_asset/global-AIDS-updat.... Accessed 26 February, 2022.
    1. Cysique LA, Maruff P, Brew BJ. Prevalence and pattern of neuropsychological impairment in human immunodeficiency virus-infected/acquired immunodeficiency syndrome (HIV/AIDS) patients across pre- and post-highly active antiretroviral therapy eras: a combined study of two cohorts. J Neurovirol. 2004;10(6):350–357. doi: 10.1080/13550280490521078 - DOI - PubMed
    1. Woods SP, Moore DJ, Weber E, Grant I. Cognitive neuropsychology of HIV-associated neurocognitive disorders. Neuropsychol Rev. 2009;19(2):152–168. doi: 10.1007/s11065-009-9102-5 - DOI - PMC - PubMed
    1. Mateen FJ, Mills EJ. Aging and HIV-related cognitive loss. JAMA. 2012;308(4):349–350. doi: 10.1001/jama.2012.8538 - DOI - PubMed
    1. Cysique L, Bain L, Brew B. Management issues in HIV-associated neurocognitive disorders. Neurobehav HIV Med. 2012;2:63. doi: 10.2147/nbhiv.s30466 - DOI