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. 2022 Jul-Sep;40(3):446-448.
doi: 10.1016/j.ijmmb.2022.03.012. Epub 2022 Apr 18.

Evaluation of antimicrobial susceptibilities of non-tuberculous mycobacteria against linezolid and tigecycline

Gunes Senol  1 , Can Bicmen  2 , Ayriz Gunduz  2 , Sevket Dereli  3 , Ahmet Erbaycu  3
Affiliations

Evaluation of antimicrobial susceptibilities of non-tuberculous mycobacteria against linezolid and tigecycline

Gunes Senol et al. Indian J Med Microbiol. 2022 Jul-Sep.

Abstract

Mycobacterial susceptibility testing is important for the management of nontuberculous mycobacteria (NTM) infections. The aim of the study is to determine the susceptibilities of tigecycline (TGC) and linezolid (LZD) against NTM. The study was carried out using stocks of NTM strains in the tuberculosis department of the microbiology laboratory. It was designed a retrospective study. LZD and TGC sensitivities of study isolates were analyzed by microdilution. Forty NTM isolates have been studied. LZD and TGC sensitivities varied according to the NTM type. It is concluded that each isolate should be individually evaluated due to variable susceptibilities to LZD and TGC.

Keywords: Antimycobacterial resistance; Linezolid; Non-tuberculous mycobacteria; Tigecycline.

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Declaration of competing interest None.

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