Hand-in-hand advances in microscopy and Plasmodium nuclear biology
- PMID: 35450787
- DOI: 10.1016/j.pt.2022.03.007
Hand-in-hand advances in microscopy and Plasmodium nuclear biology
Abstract
For 140 years, microscopy has repeatedly revolutionized the study of nucleus biology, but despite this our understanding of the evolutionarily divergent nucleus biology of Plasmodium remains limited. Here, we discuss how microscopy advances have enabled two groundbreaking studies by Simon et al. and Klaus et al. into Plasmodium nucleus biology.
Keywords: DNA replication; Plasmodium; microscopy; microtubule organizing center (MTOC); mitosis.
Published by Elsevier Ltd.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
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An extended DNA-free intranuclear compartment organizes centrosome microtubules in malaria parasites.Life Sci Alliance. 2021 Sep 17;4(11):e202101199. doi: 10.26508/lsa.202101199. Print 2021 Nov. Life Sci Alliance. 2021. PMID: 34535568 Free PMC article.
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Asynchronous nuclear cycles in multinucleated Plasmodium falciparum facilitate rapid proliferation.Sci Adv. 2022 Apr;8(13):eabj5362. doi: 10.1126/sciadv.abj5362. Epub 2022 Mar 30. Sci Adv. 2022. PMID: 35353560 Free PMC article.
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