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Review
. 2022 Mar 11;101(10):e29006.
doi: 10.1097/MD.0000000000029006.

Two cases of neurilemmoma in the nasal vestibule: A case report and literature review

Sung Jae Heo  1 , A Young Kim, Jung Soo Kim
Affiliations
Review

Two cases of neurilemmoma in the nasal vestibule: A case report and literature review

Sung Jae Heo et al. Medicine (Baltimore). .

Abstract

Rationale: Neurilemmoma is a benign tumor derived from the Schwann cells of the nerve sheath. The highest incidence of neurilemmoma occurs in the head and neck region; however, the nose and paranasal sinuses are rarely involved. Less than 4% of these tumors involve the nasal cavity and paranasal sinuses. To date, only six cases of nasal vestibule neurilemmoma have been reported.

Patient concerns: Two patients (a 32-year-old man and a 42-year-old woman) visited our clinic with complaint of a lump in the left nasal vestibule.

Diagnosis: Histopathological examination and immunohistochemical staining confirmed a neurilemmoma.

Interventions: The mass was completely removed via an intranasal approach.

Outcomes and lessons: Neurilemmoma is easy to overlook because it occurs rarely in the nasal vestibule, but neurilemmoma needs to be considered as a differential diagnosis.

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Conflict of interest statement

The authors have no funding or financial relationships to disclose, or conflicts of interest to declare.

Figures

Figure 1
Figure 1
A bulging of the left vestibule is shown in the nasal endoscope (A). Computed tomography shows a mass in the left vestibule (B). The tumor is a 1.5 cm-sized yellowish mass with a smooth surface (C). IT = inferior turbinate, S = nasal septum.
Figure 2
Figure 2
H&E staining of the tumor shows Antoni A and B patterns which are remarkable features of neurilemmoma (A, ×100). Immunohistochemical staining for S-100 protein demonstrates positive immunoreactivity in spindle-shaped tumor cells (B, ×100).
Figure 3
Figure 3
A protrusion of the left vestibule is observed in the endoscopic examination (A). Computed tomography shows a relatively well-circumscribed ovoid mass in the left nasal vestibule (B). A gross picture of the mass shows a 1.5 cm-sized yellowish tumor with a smooth surface (C).
Figure 4
Figure 4
Histology of the tumor shows Antoni A and B patterns in the H&E staining (A, ×100) and immunoreactivity for S-100 protein (B, ×100).
See this image and copyright information in PMC

References

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