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Review
. 2022 Jul 1;95(1135):20220056.
doi: 10.1259/bjr.20220056. Epub 2022 May 12.

Milestones in dosimetry for nuclear medicine therapy

Jonathan Gear  1
Affiliations
Review

Milestones in dosimetry for nuclear medicine therapy

Jonathan Gear. Br J Radiol. .

Abstract

Nuclear Medicine therapy has reached a critical juncture with an unprecedented number of patients being treated and an extensive list of new radiopharmaceuticals under development. Since the early applications of these treatments dosimetry has played a vital role in their development, in both aiding optimisation and enhancing safety and efficacy. To inform the future direction of this field, it is useful to reflect on the scientific and technological advances that have occurred since those early uses. In this review, we explore how dosimetry has evolved over the years and discuss why such initiatives were conceived and the importance of maintaining standards within our practise. Specific milestones and landmark publications are highlighted and a thematic review and significant outcomes during each decade are presented.

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Figures

Figure 1.
Figure 1.
Frequency distributions of dosimetry publications from 1950 to 2022 for I-131 (a), Ra-223 (b), Lu-177 (c) and Y-90 (d).
Figure 2.
Figure 2.
A time line showing the main milestones in dosimetry for nuclear medicine therapy
See this image and copyright information in PMC

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