Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Aug 1;47(8):692-698.
doi: 10.1097/RLU.0000000000004220. Epub 2022 Apr 22.

PET/CT Ultrasound Fusion for Percutaneous Biopsy: A Retrospective Single-Center Study and Review of the Literature

Bryce David Beutler  1 , Gilbert Whang, Hisham Tchelepi
Affiliations
Review

PET/CT Ultrasound Fusion for Percutaneous Biopsy: A Retrospective Single-Center Study and Review of the Literature

Bryce David Beutler et al. Clin Nucl Med. .

Abstract

Purpose: The aim of this study was to assess the diagnostic yield and complication rate of 18 F-FDG PET/CT ultrasound (US) fusion for percutaneous biopsy of FDG-avid lesions among patients with known or suspected malignancy.

Patients and methods: We describe the clinical, imaging, and histopathologic features of 36 patients who underwent percutaneous biopsy using real-time PET/CT US fusion. In addition, we review the literature on PET/CT US fusion. Using Medline, the following MeSH terms were searched and relevant citations assessed: "fusion imaging," "PET/CT fusion," "PET/CT-guided biopsy," "PET/US fusion," "ultrasound fusion," and "ultrasound fusion-guided biopsy."

Results: A total of 36 patients (15 men, 21 women) with known or suspected malignancy and prior PET/CT imaging underwent percutaneous biopsy of FDG-avid lesions using PET/CT US fusion between October 2014 and July 2020. Coregistration was achieved using General Electric LOGIQ E9 software. Adequate tissue for analysis was obtained in all 36 patients. Histologic evaluation revealed malignancy in 14 patients (38.9%) and nonneoplastic tissue in 22 patients (61.1%). No intraprocedural or postprocedural complications were recorded.

Conclusions: Fusion of PET/CT and US for percutaneous biopsy of FDG-avid lesions can be used to achieve excellent diagnostic yield with a low risk of complications.

PubMed Disclaimer

Conflict of interest statement

Conflicts of interest and sources of funding: none declared.

Similar articles

See all similar articles

Cited by

References

    1. European Society of Radiology (ESR). Abdominal applications of ultrasound fusion imaging technique: liver, kidney, and pancreas. Insights Imaging . 2019;10:6.
    1. Helck A, D’Anastasi M, Notohamiprodjo M, et al. Multimodality imaging using ultrasound image fusion in renal lesions. Clin Hemorheol Microcirc . 2012;50:79–89.
    1. Zhang H, Chen GY, Xiao L, et al. Ultrasonic/CT image fusion guidance facilitating percutaneous catheter drainage in treatment of acute pancreatitis complicated with infected walled-off necrosis. Pancreatology . 2018;18:635–641.
    1. Long Y, Xu E, Zeng Q, et al. Intra-procedural real-time ultrasound fusion imaging improves the therapeutic effect and safety of liver tumor ablation in difficult cases. Am J Cancer Res . 2020;10:2174–2184.
    1. Cha DI, Lee MW, Kim AY, et al. Automatic image fusion of real-time ultrasound with computed tomography images: a prospective comparison between two auto-registration methods. Acta Radiol . 2017;58:1349–1357.

Substances

LinkOut - more resources