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. 1987 Jan 15;142(1):194-9.
doi: 10.1016/0006-291x(87)90470-0.

Mass spectral analysis of complex lipids desorbed directly from lyophilized membranes and cells

D N Heller, C Fenselau, R J Cotter, P Demirev, J K Olthoff, J Honovich, M Uy, T Tanaka, Y Kishimoto
Free article

Mass spectral analysis of complex lipids desorbed directly from lyophilized membranes and cells

D N Heller et al. Biochem Biophys Res Commun. .
Free article

Abstract

Three desorption ionization techniques--laser desorption, plasma desorption and fast atom bombardment mass spectrometry--have been applied to lyophilized cells, membranes, lysed cells and various extracts. It has been shown that intact polar lipids are selectively desorbed from biological membranes by these methods and that their mass spectra provide "fingerprints" which reflect the unique biochemical composition of each class of cell or membrane.

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