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Comment
. 2022 Apr 21;82(8):1408-1410.
doi: 10.1016/j.molcel.2022.04.003.

Only solid waste, please!

Dorothee Dormann  1 , Christian Behrends  2
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Only solid waste, please!

Dorothee Dormann et al. Mol Cell. .
Free article

Abstract

To elucidate the mechanism driving selective autophagy of protein aggregates, or "aggrephagy," Ma et al. (2022) identify chaperonin TRiC subunit CCT2 as a receptor that specifically promotes the clearance of solid aggregates, but not liquid-like condensates, in a ubiquitin-independent manner.

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Declaration of interests The authors declare no competing interests.

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