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Clinical Trial
. 1987 Feb;74(2):104-5.
doi: 10.1002/bjs.1800740210.

Effect of cimetidine on prognosis after simple closure of perforated duodenal ulcer

C J Simpson, G Lamont, I Macdonald, I S Smith
Clinical Trial

Effect of cimetidine on prognosis after simple closure of perforated duodenal ulcer

C J Simpson et al. Br J Surg. 1987 Feb.

Abstract

A prospective controlled study in 60 patients undergoing simple closure of perforated duodenal ulcer demonstrated a significant (P less than 0.05) benefit following postoperative cimetidine treatment, in terms of avoiding subsequent dyspeptic symptoms and complications of peptic ulcer disease. Thus cimetidine is recommended in the follow-up management of perforated duodenal ulcers.

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