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Editorial
. 2022 Apr 17;10(4):922.
doi: 10.3390/biomedicines10040922.

Molecular Mechanisms in Lysosomal Storage Diseases: From Pathogenesis to Therapeutic Strategies

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Editorial

Molecular Mechanisms in Lysosomal Storage Diseases: From Pathogenesis to Therapeutic Strategies

Valeria De Pasquale et al. Biomedicines. .

Abstract

Lysosomal storage diseases (LSDs) are a group of metabolic diseases caused by inborn mutations of lysosomal enzymes, which lead to lysosome substrate accumulation in various cell types [...].

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Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Filocamo M., Morrone A. Lysosomal Storage Disorders: Molecular Basis and Laboratory Testing. Hum. Genom. 2011;5:156–169. doi: 10.1186/1479-7364-5-3-156. - DOI - PMC - PubMed
    1. Sun A. Lysosomal Storage Disease Overview. Ann. Transl. Med. 2018;6:476. doi: 10.21037/atm.2018.11.39. - DOI - PMC - PubMed
    1. Capper A., Epstein H., Schless R.A. Gaucher’s Disease. Report of a Case with Presentation of a Table Differentiating the Lipoid Disturbances. Am. J. Med. Sci. 1934;188:84. doi: 10.1097/00000441-193407000-00012. - DOI
    1. Seranova E., Connolly K.J., Zatyka M., Rosenstock T.R., Barrett T., Tuxworth R.I., Sarkar S. Dysregulation of Autophagy as a Common Mechanism in Lysosomal Storage Diseases. Essays Biochem. 2017;61:733–749. doi: 10.1042/EBC20170055. - DOI - PMC - PubMed
    1. de la Mata M., Cotán D., Villanueva-Paz M., de Lavera I., Álvarez-Córdoba M., Luzón-Hidalgo R., Suárez-Rivero J.M., Tiscornia G., Oropesa-Ávila M. Mitochondrial Dysfunction in Lysosomal Storage Disorders. Diseases. 2016;4:31. doi: 10.3390/diseases4040031. - DOI - PMC - PubMed

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